http://oncologywatch.blogsome.com new peer-reviewed articles about cancer research Mon, 02 Nov 2009 01:28:02 +0000 http://backend.userland.com/rss092 en Waters EA, Sullivan HW, Nelson W, Hesse BW. What is my cancer risk? How internet-based cancer risk assessment tools communicate individualized risk estimates to the public: content analysis. J Med Internet Res. 2009 Jul 31;11(3):e33.  We have all seen – and most of us have probably used – interactive Web-based tools ... http://oncologywatch.blogsome.com/2009/11/02/by-the-numbers-nci-experts-size-up-cancer-risk-websites/ Vickers AJ, Scardino PT. The clinically-integrated randomized trial: proposed novel method for conducting large trials at low cost. Trials. 2009 Mar 5;10:14. PMID: 19265515. Andrew Vickers and Peter Scardino, of Memorial Sloan-Kettering Cancer Center, propose a new method of conducting large clinical trials - the clinically integrated clinical trial. What is a ... http://oncologywatch.blogsome.com/2009/07/17/a-new-model-the-clinically-integrated-randomized-trial/ Weiss D, Naik P, Weiss R. The ‘big pharma’ dilemma: develop new drugs or promote existing ones? Nat Rev Drug Discov. 2009 Jul;8(7):533-4. Epub 2009 Jun 19. PMID: 19543223.  It makes sense: "Our results indicate that investments in R&D have a positive effect on stock prices, and ... http://oncologywatch.blogsome.com/2009/07/09/invest-in-rd-before-promoting-existing-products/ Tonelli M, Hemmelgarn B, Reiman T, et al. Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis. CMAJ. 2009 May 26;180(11):E62-71. PMCID: PMC2683210. Noting "a striking lack of data to support Health Canada’s labels and the American Society of Clinical Oncology’s guidelines for the use ... http://oncologywatch.blogsome.com/2009/06/24/meta-analysis-benefits-and-risks-of-erythropoiesis-stimulating-agents/ Idowu OE, Idowu MA. Environmental causes of childhood brain tumours. Afr Health Sci. 2008 Mar;8(1):1-4. PubMed PMID: 19357723 Something new in the world, and not welcome. From the summary: "Brain tumours hitherto said to be rare in Africans are now known to be common. They cause considerable concern ... http://oncologywatch.blogsome.com/2009/06/08/54/ This year I’m focusing on Tumor Biology and Human Genetics, with close attention to molecular diagnostics. Lots of abstracts look promising, including these: CANCER GENETICS Comen EA, Lautenberger J, McGee K et al. (Memorial Sloan-Kettering Cancer Center, National Cancer Institute.) Use of genome-wide scan in women with breast ... http://oncologywatch.blogsome.com/2009/05/16/53/ Pietropaolo V. In the face of cancer. CMAJ. 2009 Mar 17;180(6):645-6. PMID: 19289813 Photosensitive, a collective of photographers using photography as a vehicle for social change, and the Canadian Cancer Society cosponsored this online gallery and traveling exhibition of more than 400 photographs (and growing) of people with cancer. From the review ... http://oncologywatch.blogsome.com/2009/04/26/online-photography-exhibition-cancer-connections/ Wodarz D. Use of oncolytic viruses for the eradication of drug-resistant cancer cells. J R Soc Interface. 2009 Feb 6;6(31):179-86. PMID: 18664430 Dominik Wodarz, professor of Ecology and Evolutionary Biology at UC-Irvine, writes on the theoretical possibility of some day using oncolytic viruses to eradicate drug-resistant cancer cells prior to treatment ... http://oncologywatch.blogsome.com/2009/03/19/combining-oncolytic-viruses-with-targeted-therapies/ Lleonart ME, Artero-Castro A, Kondoh H. Senescence induction; a possible cancer therapy. Mol Cancer. 2009 Jan 8;8(1):3. PMID: 19133111 In normal cells, the ends of chromosomes (telomeres) tend to become shortened with each cell division. When telomeres shorten to a certain length, the cell can no longer replicate and enters senescence. ... http://oncologywatch.blogsome.com/2009/01/13/senescence-induction-as-a-possible-cancer-therapy/ McConnell P, Dash RC, Chilukuri R, et al. The Cancer Translational Research Informatics Platform. BMC Med Inform Decis Mak. 2008 Dec 24;8(1):60. PMID: 19108734 Researchers at Duke University Medical Center and SemanticBits (Herndon, Virginia) describe a new outcomes analysis tool that allows oncologists to query clinical data from geographically dispersed patients ... http://oncologywatch.blogsome.com/2009/01/06/cancer-translational-research-informatics-platform/