Melatonin and serotonin effects on gastrointestinal motility
Thor PJ, Krolczyk G, Gil K, et al. Melatonin and serotonin effects on gastrointestinal motility. J Physiol Pharmacol. 2007 Dec;58 Suppl 6:97-103. Review. PMID: 18212403
A fascinating essay/review on the therapeutic potential of these hormones for people at risk for colorectal cancer, ulcerative colitis, gastric ulcers and irritable bowel syndrome.
From the conclusion:
The intelligent modulation of the gastrointestinal motility with melatonin/serotonin on brain-gut axis may be a key point in the treatment of patients resistant to standard therapy functional disorders of GIT. In order to introduce these promising substances into the therapeutic use, basic research for the clear recognition of their interaction and function has to be performed in the nearest future.
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oncology cancer colorectal cancer
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