Breast cancer: origins and evolution
Polyak K. Breast cancer: origins and evolution. J Clin Invest. 2007 Nov;117(11):3155-63. Review. PMID: 17975657
A thoroughly up-to-date review article by an associate professor at Harvard Medical School who is a rising star in cancer genetics and the molecular basis of breast cancer. Dr. Polyak has a refreshingly clear and direct writing style:
"Despite significant advances in diagnosing and treating breast cancer, several major unresolved clinical and scientific problems remain. These are related to (a) prevention (who needs it and when), (b) diagnosis (we need more specific and sensitive methods), (c) tumor progression and recurrence (what causes it and how to predict it), (d) treatment (who should be treated and how), and (e) therapeutic resistance (how to predict, prevent, and overcome it)."
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oncology cancer breast cancer
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